• In this case report we described

  2019-05-05

  

  In this case report, we described a rare case of tumor lysis syndrome associated with the FOLFOX regimen and further stress the importance of additional prophylaxis for the huge tumor burden. Our patient\'s hyperammonemia may be due to cardiogenic shock, post cardio-pulmonary-cerebral resuscitation

• haspin inhibitor Our research in this area has

  2019-05-05

  

  Our research in this area has been focused on understanding the highly vascular nature of RCC, which has been largely attributed to loss of function of the von Hippel-Lindau (VHL) gene and resultant vascular endothelial growth factor (VEGF) over-expression, as it is an early event during tumorgenesi

• br Introduction Magnetic resonance imaging MRI

  2019-05-05

  

  Introduction Magnetic resonance imaging (MRI) has great utility in evaluating musculoskeletal tumors. However, some lesions have an appearance on MRI that make it challenging to differentiate benign from malignant lesions. Even intravenous (IV) E-64 sometimes does not allow differentiation of be

• Antenatal corticosteroids induce fetal lung maturation throu

  2019-05-05

  

  Antenatal corticosteroids induce fetal lung maturation through the same biological mechanism in low-income settings as in high-income settings and reduce the need for neonatal mechanical ventilation. Although antenatal corticosteroids might not be a so-called magic bullet as a standalone vertical in

• Second although it is an important and biologically plausibl

  2019-05-05

  

  Second, although it is an important and biologically plausible refinement, risk-factor adjustment based on lack of access to improved water in rural areas and urban slums could be open to criticism, as the authors acknowledge. The imperfect relation between access to improved water and consumption o

• br Conclusions br Acknowledgements This work was supported b

  2019-05-04

  

  Conclusions Acknowledgements This work was supported by Bloodwise, the International Myeloma Foundation and a Marie Curie Career Integration Grant from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n° [294160]. The osteoblast in normal bone physiology

• The clinical spectrum of intracranial hemorrhage is similar

  2019-05-04

  

  The clinical spectrum of intracranial hemorrhage is similar for patients treated with warfarin and dabigatran [10]. Absolute rates of intracranial hemorrhage across all sites and of both fatal and traumatic intracranial hemorrhages are lower with dabigatran than with warfarin [10]. Concomitant aspir

• Involvement of the ventricular myocardium can

  2019-05-04

  

  Involvement of the ventricular myocardium can lead to delayed conduction or anatomical obstacles that are labile to ventricular tachyarrhythmia. Arrhythmias are independently predictive of sudden cardiac death (SCD) [9]. SCD is common in patients with cardiac AL amyloidosis, and prophylactic implant

• RANK RANKL The RANK RANKL signaling pathway is

  2019-05-04

  

  RANK/RANKL: The RANK/RANKL signaling pathway is a critical component of both normal and malignant bone remodeling. RANK is a transmembrane signaling receptor and a member of the tumor necrosis receptor (TNF) superfamily that is found on the surface of OCL precursors [43,44]. RANK ligand (RANKL) is e

• br Methods br Results br Discussion The results

  2019-05-04

  

  Methods Results Discussion The results of this study demonstrate that (1) low-dose landiolol (0.5μgkg−1min−1) prevent heart rate elevation after AF ablation; (2) prophylactic administration of low-dose landiolol successfully prevented immediate AF recurrence within 3d after AF ablation with

• Concurrent with the clinical evaluation

  2019-05-04

  

  Concurrent with the clinical evaluation of the family, the genetic findings from a molecular autopsy may help to elucidate the cause of death in the decedent, as well as provide a basis for cascade genetic testing of at-risk family members. Offering cascade genetic testing to asymptomatic relatives

• To assess quality independent from quantity Imamura and

  2019-05-04

  

  To assess quality independent from quantity, Imamura and colleagues assessed dietary intake adjusted for 2000 kcal per day. An unfortunate consequence of this adjustment is that the role of unrestrained energy intake in the obesity and diabetes epidemics seems to be rendered obsolete. For example, i

• br Conclusions br Financial support

  2019-05-04

  

  Conclusions Financial support Conflict of interest Acknowledgment Introduction Cardiac resynchronization therapy (CRT) has been demonstrated to improve symptoms, quality of life, functional status, and reduce mortality and Spadin failure-related hospitalizations in patients with New Y

• caspase pathway Una de las teor as m s

  2019-04-30

  

  Una de las teorías más destacadas sobre el género lo emparenta con el proyecto que llevaron caspase pathway cabo autores alemanes como Bertold Brecht o Walter Benjamin, quienes: Ana María Amar Sánchez, teórica que propone esta línea genealógica para explicar la creación testimonial del argentino Ro

• Upper gastrointestinal bleeding secondary to peptic ulcer di

  2019-04-30

  

  Upper gastrointestinal bleeding secondary to peptic ulcer disease is a common life-threatening medical condition. However, historically, peptic ulcer disease was an uncommon ailment. The rise in the incidence of peptic ulcer disease occurred in the mid-1800s. At that time, studies in North America a

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