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More than thirty enzymes with PLA
2019-07-15

More than thirty enzymes with PLA2 activity have been described and, based on sequence similarities, they are currently classified in 16 groups, each containing several sub-groups [16]. However, based on biochemical features these enzymes are frequently grouped into six major families: secreted phos
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Celiac disease occurs in the small intestine due
2019-07-15

Celiac disease occurs in the small intestine due to the ingestion of gluten and triggers an immune response by T-cells resulting in tissue remodelling and malnutrition [6]. Earlier studies by many researchers have shown that the prolamins of gluten are the toxic agent for celiac disease, since they
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br Discussion Previous studies have reported
2019-07-15

Discussion Previous studies have reported conflicting association results between the functional variant DBH −1021C>T and PD [8], [9]. Our findings would suggest that DBH −1021C>T does not dramatically decrease the risk of disease although it may marginally affect symptomatic AAO. However, whethe
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The role of activation of
2019-07-13

The role of activation of xenosensor nuclear receptors such as PPARα, CAR, and PXR in producing hepatomegaly and liver tumors in rodents has been well-established (Klaunig et al., 2003, Lake, 2009). In the case of PPARα, the increase in liver weight results from increased peroxisomal mass and expans
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Our study found a significant association between
2019-07-13

Our study found a significant association between the degree of primary tumor lobulation and EGFR mutations status (P SC-10 of status. However, only a small portion of these previous studies included the evaluation of lobulation, and almost all of them reported no association between EGFR mutations
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br Structure of ketosteroid dehydrogenase
2019-07-13

Structure of 3-ketosteroid Δ1-dehydrogenase Overall fold — High-resolution crystal structures of Δ1-KSTD are currently available for the Δ1-KSTD1 isoenzyme from R. erythropolis SQ1 [30]. The Δ1-KSTD1 molecule has an elongated shape, and consists of two domains, an FAD-binding domain and a catalyt
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For the first time the V carinata transcriptome
2019-07-13

For the first time, the V. carinata transcriptome was analyzed and its transcript coding sequences comprehensively characterized. The non-redundant contigs encoding putative CysPs were identified and their Lisinopril dihydrate patterns in different tissues were investigated. Our study show that four
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Previous studies from our laboratory have demonstrated that
2019-07-13

Previous studies from our laboratory have demonstrated that CysLT1R mRNA and protein expression can be upregulated by T2-type cytokines (IL-13, IL-4, and IL-5) in monocytes, macrophages, and eosinophilic HL-60 cells., To our knowledge, however, there are no studies on interactions of cytokines (suc
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Signal transduction through IL c FMS ligand
2019-07-13

Signal transduction through IL-34/ c-FMS ligand receptor also leads to the differentiation, survival and, angiogenesis, proliferation, adhesion and migration of cells of the monocyte/macrophage lineage similar to that of CSF-1 through the various pathways-First is through FAK (Focal Adhesion Kinase)
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Nicotine is the main psychoactive
2019-07-13

Nicotine is the main psychoactive component of tobacco that causes addiction. Besides the regulation of the stress responses, CRF has been implicated in nicotine addiction based on several lines of evidence (Bruijnzeel and Gold, 2005, Sarnyai et al., 2001). First, acute administration of nicotine, l
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Pahlavanzadeh and Fakouri Baygi employed PC SAFT EoS
2019-07-13

Pahlavanzadeh and Fakouri-Baygi [6] employed PC-SAFT EoS to predict the cdc42 inhibitor of carbon dioxide by aqueous MEA solutions. They used the ideal form of Smith–Missen algorithm to calculate liquid phase concentrations. The results illustrate acceptable accuracies so that the AAD was achieved e
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Here we examined whether Intracellular ER
2019-07-13

Here, we examined whether Intracellular ER may mediate Cd-induced ovarian cancer proliferation. To determine this relationship, we used ICI 182,780 as a general inhibitor of ERα and ERβ. The results suggest a metalloestrogenic effect of Cd in ovarian cancer cell lines. Inconsistency with our results
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RHA is an agricultural by product obtained from the burning
2019-07-13

RHA is an agricultural by-product obtained from the burning process of rice hull [7], [8]. Rice hull is the outer layer of paddy grain. About 20% of rice hull converts into RHA when it is burnt during the 4μ8C generation processes [8], [9]. If RHA produced at less than 700 °C, it chemically possess
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To our knowledge immunohistochemical analysis for proGRP
2019-07-13

To our knowledge, immunohistochemical analysis for proGRP was done in 5 cases [9], [10], [17], [18]. Takagi-Takahashi et al. reported that the tumor alkylation of dna were positive for proGRP in one case [9]. Yamaguchi et al. also showed that tumor cells in two patients of ES/PNET with elevated ser
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br Role of cysLT signaling on various neurological complicat
2019-07-12

Role of cysLT signaling on various neurological complications which are associated with Alzheimer’s disease Alzheimer’s disease, first described in 1906 by Alois Alzheimer, is a neurodegenerative disease and a very common cause of dementia progressively leading to death. Even though years of rese
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